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Species: Mouse Monoclonal
Clone: L26
Isotype:Â IgG2a,k MW: 33 kD and 30 kD
Species Reactivity: Human
Positive Control: Tonsil
Specificity: This antibody is specific to a 33 kD polypeptide present on the majority of B cells in peripheral blood and lymphoid tissue and also with a minor component of 30 kD. No reactivity with other haematopoietic cells has been observed.
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Species: Mouse Monoclonal
Clone: Ber-H2
Isotype: IgG1,k MW: 105/120 kD
Species Reactivity: Human. Does not react with baboon and monkey
Positive Control: Hodgkin's lymphoma
Specificity: Recognizes a single chain glycoprotein of 105/120kDa, identified as CD30/Ki-1. CD30 is synthesized as a 90kDa precursor which is processed in the Golgi complex into a membrane-bound phosphorylated mature 105/120kDa glycoprotein. The CD30/Ki-1 antigen is expressed by mononuclear Hodgkin and multinucleated Reed-Sternberg cells in Hodgkin's disease, by the tumor cells of a majority of anaplastic large cell lymphomas, and by a varying proportion of activated T and B cells.
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Species: Mouse Monoclonal
Clone: UCHL1
Isotype: : IgG2a,k
Species Reactivity: Human, Rhesus Monkey. Does not react with Rat.
Positive Control: Tonsil or Lymph Node.
Specificity: This antibody reacts with a 180 kD glycoprotein of CD45 family, occurring on most thymocytes and activated T cells but only on the portion of the resting T cells. It reacts with most thymocytes, a subpopulation of resting cells within both the CD4 and CD8 subsets and mature activated T cells. This antibody shows no reactivity with normal B or natural killer cells, but reacts with granulocytes and monocytes. Though this antibody is useful to identify T-cell lymphomas and leukemia, rare staining with B cell lymphomas reported.