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Species: Mouse
Clone: 2F11
Isotype: : IgG1, Kappa
Species Reactivity: Human, Rabbit, Cat, Mouse and Rat. Does not react with dog.
Positive Control: Brain
Specificity: This antibody stains neurons (axons) of the central and peripheral nervous system. It is useful for the identification of tumors with neuronal differentiation viz. Neuroblastomas, Ganglioneuromas, Pheochromocytomas and Esthesioblastomas. The antibody cross-reacts with the NF-equivalent protein in mouse, rabbit, rat and swine. The antibody can also be utilized to discriminate between Hirschsprung's disease and allied enteric nervous system malformations.
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Species: Mouse
Immunogen: Recombinant human neurofilament protein
Clone: NF421
Isotype: : IgG1
Species Reactivity: Human, Mouse, Rat, Pig and Chicken. Others not known.
Positive Control: Brain, Neuroblastoma.
Specificity: This antibody reacts with a 200kDa protein, identified as the heavy subunit of neurofilaments (NF-H). Anti-neurofilament stains a number of neural, neuroendocrine, and endocrine tumors. Neuromas, ganglioneuromas, gangliogliomas, ganglioneuroblastomas, and neuroblastomas stain positively for anti-neurofilament. Neurofilaments are also present in paragangliomas as well as adrenal and extra-adrenal pheochromocytomas. Carcinoids, neuroendocrine carcinomas of the skin, and oat cell carcinomas of the lung also express neurofilament.
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Species: Mouse
Immunogen: PSA from human sperm plasma
Clone: A67-B/E3
Isotype: IgG1, kappa
Species Reactivity: Human. Others not known.
Positive Control: PC12 cells or normal prostate or prostate carcinoma.
Specificity: Recognizes a single protein of 33-34kDa, identified as the prostate specific antigen (PSA). This MAb is highly specific to PSA and stains prostatic secretory and ductal epithelium in both normal and neoplastic tissues.
Supplied As:Â
200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide.Â
$ 199.00
Species: Mouse
Immunogen: Recombinant human KLK3 protein
Clone: KLK3/801
Isotype: : IgG1, kappa
Species Reactivity: Human. Others not known.
Positive Control: PC12 cells or normal prostate or prostate carcinoma.
Specificity: Recognizes a single protein of 33-34kDa, identified as the prostate specific antigen (PSA). This MAb is highly specific to PSA and stains prostatic secretory and ductal epithelium in both normal and neoplastic tissues.
Supplied As: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide.
$ 199.00
Specificity & CommentsRecognizes a protein of 52kDa, identified as prostate specific acid phosphatase (PSAP). This enzyme catalyzes the conversion of orthophosphoric monoester to alcohol and orthophosphate. It is synthesized under androgen regulation and is secreted by the epithelial cells of the prostate gland. PSAP is found in non-neoplastic adult and fetal prostatic glands, primary and metastatic prostatic carcinomas. It shows no staining in granulocytes, osteoclasts, parietal cells of the stomach, liver cells, renal cell or breast carcinomas. |
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Known Applications & Suggested DilutionsFlow Cytometry (0.5-1ug/million cells)Immunofluorescence (0.5-1ug/ml) Immunohistology (Formalin-fixed) (0.5-1.0ug/ml for 30 minutes at RT) (Staining of formalin-fixed tissues requires boiling tissue sections in 10mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes) Optimal dilution for a specific application should be determined. |
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Positive ControlPC12 cells or normal prostate or prostate carcinoma |
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Key References
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Supplied As200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. |
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LimitationsThis antibody is available for research use only and is not approved for use in diagnosis. |
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WarrantyThere are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product. |
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