Actin, Smooth Muscle (Clone ACTA2/791)


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0.1 ml / 20 ug

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Species: Mouse
Immunogen: Recombinant human ACTA2 protein
Clone: ACTA2/791
Isotype: IgG2a, kappa
Species Reactivity: Tested in human. Shows a broad species reactivity.
Positive Control: Blood vessels in all tissues, smooth muscle or leiomyosarcoma.
Specificity: This monoclonal antibody is highly specific to actin from smooth muscles. This MAb does not stain cardiac or skeletal muscle; however, it does stain myofibroblasts and myoepithelial cells. In most cases of rhabdomyosarcoma, this antibody yields negative results whereas anti-muscle specific actin and myogenin are positive. Leiomyosarcomas are positive only with anti-muscle specific actin and anti-smooth muscle actin and are negative with anti-myogenin.

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