beta-Catenin (p120) (Rabbit Polyclonal)


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0.1 ml / 20 ug

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Species: Rabbit
Immunogen: A synthetic peptide from the middle of beta-Catenin (p120) protein
Clone: Polyclonal
Isotype: IgG
Species Reactivity: Human and Mouse. Others not known.
Positive Control: HeLa or MCF-7 cells. Breast carcinoma.
Specificity: Immunostaining of beta-catenin and E-cadherin is helpful in the accurate identification of ductal and lobular neoplasms, including a distinction between low-grade ductal carcinoma in situ (DCIS) and lobular carcinoma. Some rectal and gastric adenocarcinomas demonstrate diffuse cytoplasmic beta-catenin staining and a lack of membranous staining, mimicking the staining pattern observed with lobular breast carcinomas.

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