The Copper Stain Kit (For Microwave) is a rapid (2 hr) staining kit that is intended for the demonstration of copper deposits in tissue sections, most commonly in cases of suspected Wilson's disease. Wilson's disease is a rare autosomal disorder caused by decreased serum ceruloplasmin, a blood protein that transports serum copper. Ceruloplasmin deficiency leads to excessive copper accumulation in brain, eye, and liver. In the liver, hepatic copper accumulation results in fatty change, acute hepatitis, chronic hepatitis, eventually resulting in cirrhosis. Urinary copper excretion is increased.
The rubeanic acid and rhodanine stains in the Copper Stain Kit are used to stain the cytoplasmic accumulation of copper in the liver.
Copper Deposits: Light Brown to Red
Our kit is designed for staining myelin/myelinated axons and Nissil substance on formalin fixed, paraffin-embedded tissue as well as frozen tissue. Our kit is used for identifying the basic neuronal structure in brain or spinal cord sections, and contains a Cresyl Echt Violet counterstain. Using our protocol and the modified formulation, myelinated tissue can be stained in as little as 30 minutes.
Teomics offers an array of new antigen retrieval products that make immunostaining quick and easy. 4Gone is a unique antigen retrieval system that utilizes gentle heating at low temperatures, allowing you to retrieve a large variety of antigens that can't been seen with other reagents.